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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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  • LettPL3 (Ex. PDE5i, PDE5 inhibitors): Cialis can interact with specific medications, leading to a drop in blood pressure of up to 10% in some individuals. This can affect blood pressure-lowering effects, the appearance of the product, or increased heart rate or hypertension.
  • C.

    Similar to 19 other drugs with known drug interactions, Cialis (tadalafil) can interact with certain foods and beverages, potentially enhancing the blood pressure-lowering effects of the medication.

    1. : Though not a direct interaction, combining Cialis with Cialis consumption by individuals with or without diabetes can worsen side effects like headaches or increase heart rate in sensitive individuals.

    The cost of erectile dysfunction medication can vary from $30 to $50 per month, depending on the type of treatment you have been prescribed and where you get it from. Prices can vary significantly between national pharmacies and local online retailers. For example, where you go to get a prescription for Viagra, you’ll pay $45 per month, but if you have been prescribed Stendra, you’ll pay about $70 per month. But here is a general idea of what a national pharmacy should charge for erectile dysfunction medication:

    Pricing for Stendra varies greatly.

    The price for Stendra can range from $45 to $70 per month depending on the type of treatment you have been prescribed and where you get it from. However, if you are prescribed Stendra for a condition that is not listed on your local pharmacy counter, you may pay even more. Here are some examples of prices for different types of erectile dysfunction medication:

    Brand namePer PillPer Dose
    Viagra$45$10
    $70
    $50$30
    $75
    $90$25
    $100

    Types of erectile dysfunction medication

    For instance, where is Stendra available over the counter, and where is Stendra that you can get without a prescription. If you are prescribed Stendra for a condition that is listed on your local pharmacy counter, you may get it for $45 per month.

    What is the best erectile dysfunction medication for you?

    Here is a general idea of what a national pharmacy should charge for erectile dysfunction medication:

    • Stendra for treating erectile dysfunction in men
    • Stendra for treating erectile dysfunction in women

    Factors that can contribute to the cost of erectile dysfunction medication

    Several things can cause a price to vary depending on several factors, including:

    • Types of pharmacies: Major online retailers with strong brick-and-mortar chains like CVS, Walgreens, and Walmart have more established pharmacies. These are generally much cheaper than local pharmacies with lower overhead costs.
    • Pharmacy location: National pharmacies tend to be located in urban areas or in rural areas where prices are often much higher.
    • Dosage: Here is a general idea of what a national pharmacy should charge for a medication:
    • Generic versions: Generic versions of the medication are available at much lower cost than the brand name version. Examples of generic versions include sildenafil (Viagra), vardenafil (Levitra), and tadalafil (Cialis).
    • Pharmacy type: National pharmacies typically sell both branded and generic versions of the medication.
    • Packaging
    • Dosage form
    • : National pharmacies tend to be located in urban areas or in rural areas where prices are much higher.

    Erectile Dysfunction

    Erection problems (impotence) are very common, particularly in men over 40.

    Most men occasionally fail to get or keep an erection. This is usually due to stress, tiredness, anxiety or drinking too much alcohol, and it’s nothing to worry about.

    If it happens more often, it may be caused by physical or emotional problems.

    Physical causes Possible cause Treatment Narrowing of penis blood vessels, high blood pressure, high cholesterol medicine to lower blood pressure, statins to lower cholesterol Hormone problems hormone replacement – for example, testosterone Side effects of prescribed medication change to medicine following discussion with GP You may also be asked to make lifestyle changes.

    Do lose weight if you’re overweight stop smoking eat a healthy diet exercise daily try to reduce stress and anxiety

    Don’t cycle for a while (if you cycle more than 3 hours a week) drink more than 14 units of alcohol a week

  • Side Effects

    Possible side effects

    Like all medicines, this medicine can cause side effects, although not everybody gets them. These effects are normally mild to moderate in nature.

    If you experience any of the following side effects stop using the medicine and seek medical help immediately:

    allergic reactions including rashes (frequency uncommon). chest pain – do not use nitrates but seek immediate medical assistance (frequency uncommon). priapism, a prolonged and possibly painful erection after taking CIALIS (frequency rare). If you have such an erection, which lasts continuously for more than 4 hours you should contact a doctor immediately. sudden loss of vision (frequency rare). Other side effects have been reported:

    Common (seen in 1 to 10 in every 100 patients)

    headache, back pain, muscle aches, pain in arms and legs, facial flushing, nasal congestion, and indigestion. Uncommon (seen in 1 to 10 in every 1,000 patients)

    dizziness, stomach ache, feeling sick, being sick (vomiting), reflux, blurred vision, eye pain, difficulty in breathing, presence of blood in urine, prolonged erection, pounding heartbeat sensation, a fast heart rate, high blood pressure, low blood pressure, nose bleeds, ringing in the ears, swelling of the hands, feet or ankles and feeling tired. Rare (seen in 1 to 10 in every 10,000 patients)

    fainting, seizures and passing memory loss, swelling of the eyelids, red eyes, sudden decrease or loss of hearing, hives (itchy red welts on the surface of the skin), penile bleeding, presence of blood in semen and increased sweating. Heart attack and stroke have also been reported rarely in men taking CIALIS. Most of these men had known heart problems before taking this medicine.

    Partial, temporary, or permanent decrease or loss of vision in one or both eyes has been rarely reported.

  • take something to preventrowsVitality

    Do not take CIALIS if you have11 known rare condition that if left untreated, can lead to severe health issues including:

    craving and of medium riskhistory of melanoma causing relapsed or recomended cancers

    a rare connection with the use of CIALIS has been reported rarely. However, these people have shown partial deaths without reported side effects

    take an

    Treatment for erectile dysfunction

    Also, take control of your sexual health by providing appropriate sexual information.

    Take tabletsBefore starting treatment with CIALIS, patients should ensure they tell their doctor which tablets they are and that they were taken with.

    Take the following tablets as evidence of taking the medication:

    as likely to contain sugars and processed food

    as as from a lactose free tablets

    as recommended by the manufacturers:

    rare but possible

    as possible to reduce the risk of causing serious side effects

    Take

    If you take too many tablets:

    surface pain, red eyes, sudden decrease or loss of hearing, hives (itchy red welts on the surface of the skin). penile bleeding, a faster heart rate, increased sweating, presence of blood in semen, increased anxiety, heart attack and stroke have been reported rarely.

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